Drug Dose (IV) Comment
Adenosine 0.1 mg/Kg
(Max dose: 6 mg) IV
Give rapidly
No effect in 2 min:
0.2–0.3 mg/Kg
(Max dose: 12mg)
Albuterol MDI: 4–8 puffs q 20 min with spacer or through ETT
Neb: 2.5 mg (<20 Kg) and 5 mg (> 20 Kg) q 20 min
Continuous Neb: 0.5 mg/Kg/hr
Asthma, Anaphylaxis,
Hyperkalemia
Amiodarone 5 mg/Kg IV/IO* Give rapid bolus for V. Fib/pulseless VT
Give over 20–60 min for SVT and ventricular dysrhythmias
Atropine 0.02 mg/Kg IV
(may give ETT)
Max dose: 0.5 mg (child)
1 mg (adolescent)
Calcium Chloride 10%** 20 mg/Kg IV Give slowly
(Max. rate 100 mg/min)
Max dose: 1 Gm/dose
Give in central line if
available**
Dexamethasone 0.6 mg/Kg PO/IM/IV Max dose: 16 mg
Dextrose 500 mg/Kg IV 1–2 ml/Kg D50W Child
2–4 ml/Kg D25W Infant
2–3 ml/Kg D10W NICU
Epinephrine (Anaphylaxis) Anaphylaxis
IM: 0.01 mg/Kg
(0.01 ml/Kg) 1:1,000
Anaphylaxis Max dose:
0.3 mg or 0.3 ml
Epinephrine (Code)

PICU/PEDS
IV/IO*: 0.01–0.03 mg/
Kg 1:10,000 concentration
ETT: 0.1 mg/Kg 1:1,000
concentration

NICU
1:10,000 only all routes
IV/IO: 0.1–0.3 ml/Kg
(0.01–0.03 ml/Kg)
1:10,000
ETT: 0.5–1 ml/Kg
(0.05–0.1 mg/Kg) 1:10,000

Repeat q 3–5 min. for
code
Epinephrine (Racemic) 0.25–0.5 ml racemic
solution (2.25%) mixed in
3 ml saline via inhalation
3 ml of 1:1000
epinephrine mixed with
3 ml saline via inhalation
is alternative if racemic epi
not available
Croup
Flumazenil 0.01 mg/Kg IV
(Max dose: 0.2 mg)
Give over 15 seconds
May repeat at 1 minute
intervals up to 4 times
Max total dose: 0.05 mg/
Kg or 1 mg, whichever is
lower
Furosemide 0.5–1 mg/Kg IV Congestive heart failure
Use lower dose in
furosemide naive patients
Hydrocortisone 2 mg/Kg IV bolus Adrenal insuffi ciency,
catecholamine refractory
shock
Insulin (regular) 0.05–0.1 Units/Kg bolus
IV or SQ
0.05–0.1 Units/Kg/hr
infusion
Diabetic Ketoacidosis
(Infusion preferred to bolus dosing)
Lidocaine 2% 1 mg/Kg IV/IO* May repeat dose in
10–20 min.
Magnesium Sulfate 25 mg/Kg IV/IO* Give over 10–20 min; faster in Torsades de Pointes
Max dose: 2 Gm
Methylprednisolone 2 mg/Kg IV/IO/IM Status Asthmaticus,
Anaphylaxis
Max dose: 60 mg; use
only acetate salt for IM
Naloxone 0.01 mg/Kg IV/ET Titrate to effect
Max dose: 2 mg
Nicardipine 0.5–4 mcg/Kg/min IV Hypertensive urgency/Emergency
Sodium Bicarbonate 1 mEq/Kg IV Use 1 mEq/ml for > 6 months
Use 0.5 mEq/ml for < 6 months
Terbutaline 10 mcg/Kg SQ q 15 min
0.1–10 mcg/Kg/min IV
Refractory status
Asthmaticus
Max dose: 0.4 mg
Vasopressin 0.5 units/Kg IV/IO* Max dose: 40 units

** Central line preferred
*** Central line preferred, but short duration peripheral IV acceptable