Jonathan M. Klein, MD
Peer Review Status: Internally Peer Reviewed

Suggested Initial Respirator Settings

Suggested Initial Respirator Settings
Condition Rate1 (Breaths/Min) PIP2 (CM H2O) PEEP (CM H2O) FiO2
RDS 30-40 16-24 4-6 *
Primary Apnea 15-25 14-20 3-4 *
Congestive Heart Failure (Pulmonary Edema) 15-25 18-22 4-6 *
Meconium Aspiration Syndrome 30-60 24-30 4-6 **
Pneumonia 30-40 24-30 6-8 **

(1) Inspiratory Time--All neonates should have aninspiratory time of 0.3 to 0.5 seconds and an expiratory time not less than 0.5 seconds unless the rate exceeds 60/minute. At rates above 60, use equal inspiratory and expiratory times (I:E=1:1).

(2) Confirmation of correct PIP should always be determined by appropriate chest wall excursion.

* Adjust FiO2 as indicated to maintain oxygen saturation 85%-95% (PaO2 50-70mm Hg).

** Because of the risk of right to left shunting (PFC), the FiO2 in this condition is adjusted to maintain the oxygen saturation greater than 95% (PaO2 > 80mm Hg) in term infants.